Department of Biology
Biology Faculty Profile
Iain Shepherd
Associate Professor
iain.shepherd@emory.edu
Office Phone: 404-727-2632 | Lab Phone: 404-727-2686
Office Room: Rollins 1131
Office Address: Emory University, Department of Biology, O. Wayne Rollins Research Center, 1510 Clifton Road NE, Atlanta , GA 30322
Lab Room: Rollins 1180
Lab Website

Research Area:
Genetics, Cell, and Developmental Biology
Neuroscience

Graduate Program Affiliation:
Biochemistry, Cell & Developmental Biology
Genetics and Molecular Biology

Degree:

B.Sc. with Honors, Imperial College of Science Technology and Medicine, University of London, UK and Associateship of the Royal College of Science, London, UK, 1990
Ph.D., University of Oxford, 1994

My lab studies the genetic basis of the development of the vertebrate intestinal nervous system, which is know as the enteric nervous system (ENS). We use the zebrafish model system for our studies. The ENS is the largest most complicated subdivision of the peripheral nervous system and is completely derived from neural crest stem cells (NCSC). The lab is interested in determining what genes are involved in the specification of the NCSC that form the ENS. We are also interested in determining what molecules are involved patterning the migration of NCSC in the intestine. We use genetic, cell biological and embryological experimental techniques in our studies. These studies are clinically important. Hirschsprung's disease is a pediatric ENS condition that affects 1 in 5000 live births the cause of which is only partly understood.


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